Resources

CRISPR Gene Editing Services

CRISPR Gene Editing Services

At Sampled (sampled.com), we offer gene editing services to make genetically modified human pluripotent stem cells (iPSCs and hESCs) for your research.

Source Cell and Reprogramming Services Flyer

Source Cell and Reprogramming Services

Sampled offers a complete service list that can take you from source cells to fully characterized induced pluripotent stem cells. We are also home to the stem cell repositories for NINDS (bioq.nindsgenetics.org) and NIMH (nimhgenetics.org) and these cells are availabe to research (commercial and non profit) world wide.

NINDS Human Cell and Data Repository Flyer

NINDS Human Cell and Data Repository

The National Institute of Neurological Disorders and Stroke (NINDS) is committed to providing well characterized cell sources to academic and industry investigators to advance the study of neurological disorders. Cell sources currently include fibroblasts and/or induced pluripotent stem cells for Alzheimer’s Disease, Amyotrophic Lateral Sclerosis (ALS), Frontotemporal Lobar Degeneration (FTD), Huntington’s Disease, Parkinson’s Disease, and healthy controls.

iPSC differentiation into neuronal cells

iPSC differentiation into neuronal cells

iPSCs can be used as powerful tool in regenerative medicine, drug discovery,
therapeutic disease modelling, and to study development. We are happy to
announce that at Sampled, in addition to iPSC reprogramming and gene editing
services, we now offer iPSC-derived neuronal progenitor cell (NPC) differentiation
services. NPCs are a progenitor population of cells that can differentiate into neuronal populations and can be used for studying physiology, disease phenotypes and drug testing.

Using a robust and reproducible method developed by Dr. Sally Temple at NeuroCell, iPSC-derived NPCs are generated in culture using guidance factors such as dual SMAD inhibition, to recapitulate the development of the forebrain and create NPCs that can be differentiated into forebrain neurons.

NIMH Repository and Genetics Resource

NIMH Repository

The purpose of the NIMH Stem Cell Center is to provide a resource for postnatal-to-
adult human control and patient-derived cells and their reprogrammed derivatives, including induced pluripotent stem cells (iPSCs). This Center supports investigators engaged in stem cell-based research relevant to mental disorders, including but not limited to anxiety disorders, attention deficit hyperactivity
disorder, autism spectrum disorders, bipolar disorder, borderline personality disorder, depression, eating disorders, obsessive-compulsive disorder, panic disorder, post-traumatic stress disorder, and schizophrenia. The capabilities of the Stem Cell Center include derivation, validation, banking and distribution of a wide
variety of cells such as primary source cells from human tissue, iPSCs or similar reprogrammed cells.

Stem Cell Research Brochure

As part of the processing services at Sampled we offer a variety of stem cell and gene editing services.

Stem cells and iPSCs can be used as a powerful tool in regenerative medicine, drug discovery, disease modelling, and to study development.

At Sampled we strive to provide researchers with highly characterized, functional cells that can be purchased “off the shelf” or reprogrammed/edited to suit your needs.

Strategies for generating the highest quality isogenic IPSC lines

ISBER 2022

If you missed Dr Azadeh Jadali’s talk at ISBER you can read the highlights here

SARS-CoV-2 Sequencing, Polygenic Risk Scores, and Precision Medicine: High-throughput Solutions

ISBER 2022 Talk snapshot

If you missed Dr Christian Bixby’s talk at ISBER 2022 you can read the highlights here

Innovative strategies for protecting sample integrity with an eye towards the future

Plenary talk at ISBER 2022

If you missed Dr Michael Sheldon’s plenary talk at ISBER 2022, you can read the highlights here

Build your biobanking house on solid footing

ISBER 2022 Talk

Corporate Workshop with Dr Michael Sheldon (Sampled), Dr Luke Sterwart (Fluidigm) and Dr Michael Denton (Indiana University). Presented at ISBER 2022 on 17/05/2022.

If you missed the workshop with Sampled and Fluidigm at ISBER 2022, you can read the highlights here.

Corporate Brochure

Any Sample, Every Answer

Learn more about who we are, the services we provide and where it all began.