Peripheral blood mononuclear cells (PBMCs) are a fundamental component of many important fields of study, such as immunology, and are central to modern treatment strategies like CAR T-cell therapy1,2. These cells are also used for drug screening, diagnostics, and biomarker discovery, however, variations in PBMC isolation and processing can significantly impede research efforts. Almost all […]
The Critical Role of Pre-Analytical Work in Ensuring Data Integrity in Clinical Trials and Longitudinal Studies
The quality and consistency of pre-analytical processes are crucial for data integrity, ultimately determining the success of clinical trials and longitudinal studies. Given the significant time and financial investments in these studies1,2, maintaining high-quality and consistent samples is essential to avoid compromised sample integrity, resulting in inaccurate data and invalid or inconclusive study outcomes. However, […]
Disaster Recovery – Why build it into your Business Plan?
Disaster recovery is the process of preparing for and recovering from potential interruptions in an organization’s stability storage operations. This involves taking steps to ensure the preservation of valuable samples in the event of an unforeseen incident such as power failure, equipment malfunction or natural disasters. In this article we cover the major reasons why […]
High Performance Partnerships in Clinical Trials: Triangulating Success between CROs, Lab Services, and Sponsors
Introduction: Due to the complexity of clinical trials, high performance partnerships are paramount. The crucial role of Clinical Research Organizations (CROs) and sponsors is well established, but an underutilized relationship exists with specialist lab services. Picture a triangle, where each corner represents a pivotal partner in this relationship: the CRO, Lab Services, and Sponsor. How […]
Stability Storage – 3 Powerful Reasons to Outsource
Stability storage is a critical component of the pharmaceutical, medical device and life science industries. It plays a crucial role in early-stage product development to late-stage follow-up stability studies. These studies are critical because they provide evidence on how the quality of a drug substance/product/packaging varies with time under the influence of environmental factors such […]
Comprehensive Guide for Researchers: 5 Major Research Applications of Saliva Samples
Saliva samples are a powerful tool in diagnostics and research, providing a non-invasive and easily obtainable medium for a wide range of bioanalytical studies. This comprehensive guide dives into five major research applications of saliva samples and discusses in-depth best practices for maintaining sample integrity through high quality sample collection kitting. Genetic Analysis & Genome-Wide […]