iPSC differentiation into neuronal cells
iPSCs can be used as powerful tool in regenerative medicine, drug discovery,
therapeutic disease modelling, and to study development. We are happy to
announce that at Sampled, in addition to iPSC reprogramming and gene editing
services, we now offer iPSC-derived neuronal progenitor cell (NPC) differentiation
services. NPCs are a progenitor population of cells that can differentiate into neuronal populations and can be used for studying physiology, disease phenotypes and drug testing.
Using a robust and reproducible method developed by Dr. Sally Temple at NeuroCell, iPSC-derived NPCs are generated in culture using guidance factors such as dual SMAD inhibition, to recapitulate the development of the forebrain and create NPCs that can be differentiated into forebrain neurons.