Cellular Services

Cell Sample Processing

Sampled’s iPSC services offer a versatile range of solutions for researchers:

• iPSC Reprogramming: Efficiently transform differentiated cells into iPSCs, backed by robust QC.
• iPSC Gene Editing: Precise modifications using Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-Cas9 technology, with a free control line.
• iPSC Expansion: We can expand your iPSCs to ensure that you never run out of vials. 
• Neural Progenitor Cell (NPC) Differentiation: Induce iPSCs into NPCs with thorough QC and readily available cells in stock.
• iPSC QC: Comprehensive QC for high-quality iPSC products, supporting research endeavors.

• PBMC Isolation
• Lymphoblastoid cell lines (LCL) Generation & Expansion
• Fibroblast Generation and Expansion

iPSC Services

Sampled’s iPSC services offer a versatile range of solutions for researchers:

• iPSC Reprogramming: Efficiently transform differentiated cells into iPSCs, backed by robust QC.
• iPSC Gene Editing: Precise modifications using Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-Cas9 technology, with a free control line.
• iPSC Expansion: We can expand your iPSCs to ensure that you never run out of vials. 
• Neural Progenitor Cell (NPC) Differentiation: Induce iPSCs into NPCs with thorough QC and readily available cells in stock.
• iPSC QC: Comprehensive QC for high-quality iPSC products, supporting research endeavors.

Sampled provides personalized iPSC services to meet specific client needs, encompassing iPSC reprogramming, gene editing, expansion, QC, and NPC differentiation. The iPSC reprogramming service accommodates various source materials with timelines ranging from 3-6 months. iPSC gene editing is customized to client specifications, involving advanced methods and QC checks. Expansion involves expanding and storing many vials of high-quality iPSCs. NPC differentiation services are tailored to client requirements, with a 3-4 month turnaround for 16-20 vials of neural progenitor cells. Additionally, Sampled offers diverse QC options for iPSCs to ensure client preferences are met.

• iPSC Reprogramming
• iPSC Gene Editing
• iPSC Expansion
• Neural Progenitor Cell (NPC) differentiation
• iPSC Quality Control

Histology

Histology plays a pivotal role in clinical and academic studies, offering insights into tissue anatomy, cell constituents, and marker expression. At Sampled, our comprehensive histological processing service aids in understanding your sample, from primary biopsy to expertly imaged slides and analysis, streamlining the entire histology pipeline.

Samples are received, cataloged, stored, and processed by fixing, permeabilizing, embedding, sectioning, and staining. High-quality 40X digital images are captured using Olympus VS120 microscopes and securely stored for analysis. Following imaging, samples can be stored, returned to the client, or sent for analysis by a pathologist, allowing flexibility to match client needs at any stage of the process.

Cell Line Repositories

Sampled is the sole host and distributor of key biospecimen collections to scientists for a number of publicly available biorepositories. Biomaterials can be requested by scientists from small academic groups all the way up to large pharmaceutical organizations.

The samples in the publicly available biorepositories at Sampled have been collected, expanded, and stored with the intent of making them available to the wider scientific community for their research. Samples have been built over many years and come from sources like national institutes, research foundations, and companies.