Development and Validation of a High-Throughput CAP/CLIA-Compliant Laboratory-Developed Test for Comprehensive Genomic Profiling
Multiomics
Poster
Poster overview
Development update and interim performance: FFPE solid-tumor workflow
Explore the development and interim performance of Sampled’s high-throughput comprehensive genomic profiling (CGP) laboratory-developed test (LDT), integrating DNA analysis and RNA fusion detection into a single workflow.
This poster presents early validation results using FFPE tumour samples, highlighting assay performance, analytical capabilities and the next steps towards a scalable, CAP/CLIA-compliant clinical test.
In this poster you’ll learn
- How Sampled is developing an integrated DNA and RNA workflow for comprehensive genomic profiling
- Key performance results for sequencing coverage, uniformity and reproducibility
- How the assay performs in detecting RNA fusions, microsatellite instability (MSI) and copy number variations (CNVs)
- The challenges and considerations involved in developing a high-throughput clinical LDT
- The next steps for analytical validation, workflow automation and clinical implementation
Authors
Rwik Sen, PhD
Jonathan H. Schultz, PhD
Bo Wang, PhD
Yan Ding, PhD
Michelle T. Carlson, PhD
Caroline MH. Mitchell, PhD
Shareef A. Nahas, PhD
Poster Presentation at AMP 2026
Attending AMP 2026? View this poster, presented by Sampled’s own Rwik Sen
Friday, November 13th
9:15 AM – 10:15 AM
Exhibit & Poster Hall – Poster ST018
Category: Solid Tumors
