
PacBio Long-Read Sequencing
Now More Accessible
Large-scale infrastructure with pricing that adapts to your project
Long-read sequencing is essential for generating high-fidelity, structurally comprehensive genomic data. Powered by the PacBio Revio platform, recognized as a best-in-class system for HiFi long reads, Sampled operates five Revio instruments in-house to support large-scale programs. By combining advanced sequencing technology with robust operational scale and infrastructure, we deliver cost-effective long-read sequencing at the quality and throughput today’s research demands.
Why Work with Sampled?
High Throughput Capacity
Sampled operates one of the highest‑throughput long‑read sequencing centers in North America, powered by five PacBio Revio instruments running at scale.
Dedicated Project Management
Every project begins with a dedicated Project Manager who guides you from sample submission through data delivery, ensuring consistent communication and smooth execution.
Certified PacBio Service Provider
Our close partnership with PacBio enables rapid scaling, efficient workflows, and fast turnaround times backed by validated best practices.
End‑to‑End Quality Under One Roof
From DNA extraction to library prep and sequencing, Sampled’s integrated long‑read workflow ensures high‑quality results with rigorous QC at every step.
Proven Expertise
Sampled supports one of the world’s largest human health research efforts—the Million Veterans Program—using long‑read whole‑genome sequencing at massive scale.
CAP/CLIA Accredited
As a CAP/CLIA‑accredited laboratory, Sampled meets the highest standards for reliability and quality through regular inspections, validated test systems, and strict quality controls.
Benefits of PacBio HiFi Long Read Sequencing
Exceptional accuracy:
- Highly reliable variant calls
- Fewer errors in repetitive or GC-rich regions
- Cleaner assembly
Best-in-class structural variant detection:
- Large SVs
- Inversions
- Translocations
- Copy-number changes
Uniform coverage:
- Less GC bias
- More consistent depth
- Better representation of difficult regions
Haplotyping and phasing made easy:
- Phase variants across long distances
- Separate maternal and paternal haplotypes
Methylation Calling:
- Includes the detection of 5-methylcytosine (5mC) in CpG contexts directly from sequencing data
Secure Your Sequencing Today
Learn more about Sampled and our services
Meet the team
Within our Executive Team alone we have over 180 years of cumulative experience in life sciences and healthcare, we know how to take care of your samples
Clients & Partners
We serve as the federal biorepository for four NIH institutes and multiple foundations.
Careers at Sampled
We’re always on the look out for the right people to make Sampled stronger. View vacancies here

